Structure-based design & synthesis of bioactive molecules
Computational study of biomolecular structure & dynamics
Thanos Papakyriakou, PhD
Short Bio
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Thanos was born in 1975 in Athens. He received a BSc in Chemistry (1999), MSc (2001) and PhD (2004) from the Department of Chemistry, National and Kapodistrian University of Athens. Dr. Papakyriakou received scholarships for his PhD studies at NCSR “Demokritos”, for post-doctoral studies at the University of Patras (2011, IKY scholarship), as well as two personal grants “Support of Postdoctoral Researchers” from G.S.R.T. (2012) and recently from H.F.R.I. (2018).
Since Sep. 2018, he works as a senior researcher at the Institute of Biosciences & Applications, NCSR “Demokritos”. His main research field is the design, synthesis and biological evaluation of bioactive molecules. Our group employs molecular simulations to understand structure-activity relationships and biomolecular function, in conjunction with chemical synthesis of small-molecule inhibitors and biophysical methods to study ligand binding.
His main national collaborators, among others, are Dr. Efstratios Stratikos (Protein Chemistry) and Dr. Dionisios Vourloumis (Biological Chemistry) at NCSR “Demokritos”, Prof. Georgios Spyroulias (Protein NMR) and Constantinos Stathopoulos (Biology of proteins and RNA) at the University of Patras, as well as Dr. Petros Giastas (Protein crystallography, Pasteur Institute) and Dr. Dimitrios Beis and Dr. Constantinos Tamvakopoulos (Pharmacology, BRFAA).
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